4-Methylbenzylidene camphor
CAS No. 36861-47-9
4-Methylbenzylidene camphor( 4-MBC | Enzacamene )
Catalog No. M20885 CAS No. 36861-47-9
4-Methylbenzylidene camphor is an ultraviolet light blocker used in cosmetics and sunscreen preparations specifically UV B radiation also has estrogenic activities.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 500MG | 49 | In Stock |
|
| 1G | 81 | In Stock |
|
Biological Information
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Product Name4-Methylbenzylidene camphor
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NoteResearch use only, not for human use.
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Brief Description4-Methylbenzylidene camphor is an ultraviolet light blocker used in cosmetics and sunscreen preparations specifically UV B radiation also has estrogenic activities.
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Description4-Methylbenzylidene camphor is an ultraviolet light blocker used in cosmetics and sunscreen preparations specifically UV B radiation also has estrogenic activities.
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In VitroCell Proliferation AssayCell Line:HTR8/SVneo cells Concentration:0, 5, 10, 20, 50, 100, 200, and 400 μM Incubation Time:48 hResult:Dose-dependently inhibited cell proliferation of HTR8/SVneo cell.Apoptosis Analysis Cell Line:HTR8/SVneo cells Concentration:10, 20, 50 μMIncubation Time:48 hResult:Early and late apoptotic cells was significantly increased at 20 μM and 50 μM. Cell Cycle Analysis Cell Line:HTR8/SVneo cells Concentration: 5, 10, 20, 50 μM Incubation Time:48 h Result:Gradually increased the proportion of cells in the SubG1 phase. Cell Invasion Assay Cell Line:HTR8/SVneo cells Concentration:50 μM Incubation Time:48 hResult:Revealed a significant reduction of 81.5% in invasivenes0.Western Blot Analysis Cell Line:HTR8/SVneo cells Concentration:50 μM Incubation Time:0, 5, 15, 30, 60, 120 min Result:The phosphorylation of AKT and its downstream kinase protein, P70S6K, peaked at 5 and 15 min, respectively, subsequently decreased after 30 min, and then reactivated at 120 min RT-PCR Cell Line:HTR8/SVneo cells Concentration:20, 50 μM Incubation Time:24 h Result:Significantly increased the expression of semaphorin 6 A (SEMA6 A), GPR56, integrin subunit beta 4 (ITGB4), EPHB4, neuropilin 1 (NRP1).
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In Vivo——
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Synonyms4-MBC | Enzacamene
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PathwayEndocrinology/Hormones
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TargetAChR
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RecptorAChE
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Research Area——
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Indication——
Chemical Information
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CAS Number36861-47-9
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Formula Weight254.37
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Molecular FormulaC18H22O
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Purity>98% (HPLC)
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SolubilityDMSO:47 mg/mL (184.77 mM)
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SMILESCc1ccc(C=C2C(=O)C3(C)CCC2C3(C)C)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Stefan D Kirsten M Margret S et al. Estrogen Target Gene Regulation and Coactivator Expression in Rat Uterus after Developmental Exposure to the Ultraviolet Filter 4-Methylbenzylidene Camphor[J]. Endocrinology(5):5.
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